Abstract: In the sixteenth century, the poor made up a significant proportion of the population and were a major worry for the public powers. From 1518, the Cortès recommended the reorganisation of charity. In light of this, we consider two different attempts at assisting the poor : the hospital of San Juan de Dois, opened in Granada in 1537, and the alms houses of Miguel Ginginta, which began to be created in 1580. We focus on the way they functioned and on their evolution.