Abstract: The aim of this article is to examine the role of mobile money in the adoption of e-commerce by firms in Cameroon. The analysis focuses on a sample of 145 439 firms, taken from the 2nd General Business Census (INS, 2018). Results obtained using probit with multinomial logit selection bias correction, reveal that mobile money stimulates e-commerce adoption among firms. In addition, firm size, level of education and improved institutional environment also significantly boost e-commerce.